Output

List of publications:

Type Bibliographic details
Peer-reviewed publicationBaert, M., Wicht, K., Hou, Z., Szucs, R., Prez, F. D., & Lynen, F. (2020). Exploration of the selectivity and retention behavior of alternative polyacrylamides in temperature responsive liquid chromatography. Analytical Chemistry, 92(14), 9815-9822. https://doi.org/10.1021/acs.analchem.0c01321
Peer-reviewed publicationRusso, G., L. Grumetto, R. Szucs, F. Barbato, and F. Lynen. (2018). “Screening Therapeutics According to their Uptake Across the Blood-Brain Barrier: A High Throughput Method Based on Immobilized Artificial Membrane Liquid Chromatography-Diode-Array-Detection Coupled to Electrospray-Time-of-Flight Mass Spectrometry.” European Journal of Pharmaceutics and Biopharmaceutics 127: 72-84. https://doi.org/10.1016/j.ejpb.2018.02.004
Peer-reviewed publicationRusso, G., Grumetto, L., Baert, M., & Lynen, F. (2021). Comprehensive two-dimensional liquid chromatography as a biomimetic screening platform for pharmacokinetic profiling of compound libraries in early drug development. Analytica Chimica Acta, 1142, 157-168. https://doi.org/10.1016/j.aca.2020.11.003
Peer-reviewed publicationRusso, G., Ermondi, G., Caron, G., Verzele, D., & Lynen, F. (2021). Into the first biomimetic sphingomyelin stationary phase: Suitability in drugs’ biopharmaceutic profiling and block relevance analysis of selectivity. European Journal of Pharmaceutical Sciences, 156. https://doi.org/10.1016/j.ejps.2020.105585
Peer-reviewed publicationFlavio A. Franchina, Lena M. Dubois, and Jean-Franco̧is Focant
Anal. (2020). n-Depth Cannabis Multiclass Metabolite Profiling Using Sorptive Extraction and Multidimensional Gas Chromatography with Low- and High-Resolution Mass Spectrometry
Chem. 2020, 92, 10512−10520. https://doi.org/10.1021/acs.analchem.0c01301
Peer-reviewed publicationBen Henderson, Dorota M Ruszkiewicz, Max Wilkinson, Jonathan D Beauchamp, Simona M Cristescu, Stephen J Fowler, Dahlia Salman, Fabio Di Francesco, Gudrun Koppen, Jens Langejürgen, Olaf Holz, Andria Hadjithekli, Sergi Moreno, Michele Pedrotti, Pablo Sinues, Gitte Slingers, Michael Wilde, Tommaso Lomonaco, Delphine Zanella, Renato Zenobi, Jean-François Focant, Stanislas Grassin-Delyle, Flavio Antonio Franchina, Michaela Mal ́askov, Pierre-Hugues Stefanuto, Giovanni Pugliese, Christopher Mayhew and C L Paul Thomas. A benchmarking protocol for breath analysis: the peppermint experiment. J. Breath Res. 14 046008. https://doi.org/10.1088/1752-7163/aba130
Peer-reviewed publicationFlavio Antonio Franchina, Pierre-Hugues Stefanuto, Delphine Zanella, Eliane Lazzari, Jean-François Focant. (2020). Investigating aroma diversity combining purge-and-trap, comprehensive two-dimensional gas chromatography, and mass spectrometry. J Sep Sci 2020;43:1790–1799. https://doi.org/10.1002/jssc.201900902
Peer-reviewed publicationBenedikt A. Weggler, Lena M. Dubois, Nadine Gawlitta, Thomas Groger, John Moncur, Luigi Mondello, Steven Reichenbach, Peter Tranchida, Zhijun Zhao, Ralf Zimmermann, Mariosimone Zoccali, Jean-Francois Focant. (2020). A unique data analysis framework and open source benchmark dataset for the analysis of comprehensive two-dimensional gaschromatography software. https://doi.org/10.1016/j.chroma.2020.461721
Peer-reviewed publicationBenedikt A. Weggler, Beate Gruber and Jean-François Focant. (2020). Comprehensive two-dimensional gas-chromatography to study the human exposome: Current trends and perspectives. Current Opinion in Environmental Science & Health 2020, 15:16 – 25. https://doi.org/10.1016/j.coesh.2020.02.011
Peer-reviewed publicationFlavio Antonio Franchina, Eliane Lazzari, George Scholl and Jean-François Focant. (2019). Assessment of a New GC-MS/MS System for the Confirmatory Measurement of PCDD/Fs and (N)DL-PCBs in Food under EU Regulation. Foods, 8, 302. https://doi.org/10.3390/foods8080302
Peer-reviewed publicationV. Pepermans, M. T. Rerick, B. Degreef, S. Eeltink, S. G. Weber, G. Desmet. (2020). Column-in-Valve Designs to Minimize Extra-Column Band Broadening; Journal of Chromatography A. Accepted manuscript: Manuscript number: JCA-20-1683R1.
Peer-reviewed publicationHegade, R. S., Chen, K., Boon, J. -., Hellings, M., Wicht, K., & Lynen, F. (2020). Development of an achiral-chiral 2-dimensional heart-cutting platform for enhanced pharmaceutical impurity analysis. Journal of Chromatography A, 1628. https://doi.org/10.1016/j.chroma.2020.461425
Peer-reviewed publicationZ. Zhou, M. De Pra, F. Steiner, G. Desmet, S. Eeltink. (2020). Assessing effects of ultra-high-pressure liquid chromatography instrument configuration on dispersion, system pressure, and retention. J. Chromatogr. A, 1634, 461660. https://doi.org/10.1016/j.chroma.2020.461660
Peer-reviewed publicationRusso, G., Barbato, F., Grumetto, L., Philippe, L., Lynen, F., & Goetz, G. H. (2019). Entry of therapeutics into the brain: Influence of exposed polarity calculated in silico and measured in vitro by supercritical fluid chromatography. International Journal of Pharmaceutics, 560, 294-305. https://doi.org/10.1016/j.ijpharm.2019.02.008
Peer-reviewed publicationHegade, R. S., & Lynen, F. (2019). Chiral stationary phase optimized selectivity supercritical fluid chromatography: A strategy for the separation of mixtures of chiral isomers. Journal of Chromatography A, 1586, 116-127. https://doi.org/10.1016/j.chroma.2018.12.008
Peer-reviewed publication
Flavio A. Franchina, Delphine Zanella, Thibaut Dejong, Jean-François Focant. (2021). Impact of the adsorbent material on volatile metabolites during in vitro and in vivo bio-sampling. Talanta 222 (2021) 121569. https://doi.org/10.1016/j.talanta.2020.121569
Peer-reviewed publicationT. Themelis, J. De Vos, J.L. Dores-Sousa, S. Eeltink, Engineering solutions for flow control in microfluidic devices for spatial multi-dimensional liquid chromatography. Sensors & Actuators B: Chemical 320 (220) 128388
Peer-reviewed publicationZ. Zhou, M. De Pra, F. Steiner, G. Desmet, S. Eeltink, Assessing the effects of ultra-high-pressure liquid chromatography instrument configuration on dispersion, system pressure, and retention. J. Chromatography A 1634 (2020) 461660
Peer-reviewed publicationJ.L. Dores-Sousa, H. Terryn, S. Eeltink, Morphology optimization and assessment of the performance limits of high-porosity nanostructures polymer monolithic capillary columns for proteomic analysis. Analytical Chimica Acta 1124 (2020) 176-183
Peer-reviewed publicationJ. De Vos, M.Dams, K. Broeckhoven, G. Desmet, B. Horstkotte, S. Eeltink. Prototyping of a microfluidic chip and its application in heart-cut strong-cation-exchange-reversed-phase liquid chromatography coupled to nanoelectrospray mass spectrometry for targeted proteomics. Analytical Chemistry 92 (2020) 2388-2392
Peer-reviewed publicationJ. De Vos, G. Baron, M.J. Wirth, H. Terryn, E.R. Kaal, S. Eeltink. Evaluation of particle and bed integrity of aqueous size exclusion columns packed with sub-2 micrometer particles operated at high pressure. Journal of Chromatography A 1621 (2020) 461064
Peer-reviewed publicationTowards spatial comprehensive three-dimensional liquid chromatography: a tutorial review. Analytica Chimica Acta 2020, in pressEnhancing protein discoverability by data independent acquisition assisted by ion mobility mass spectrometry.
Nys G, Nix C, Cobraiville G, Servais AC, Fillet M.Talanta. 2020 Jun 1;213:120812. doi: 10.1016/j.talanta.2020.120812.
Peer-reviewed publicationEnhancing protein discoverability by data independent acquisition assisted by ion mobility mass spectrometry.
Nys G, Nix C, Cobraiville G, Servais AC, Fillet M.Talanta. 2020 Jun 1;213:120812. doi: 10.1016/j.talanta.2020.120812.
Peer-reviewed publicationHyphenation of capillary zone electrophoresis with mass spectrometry for proteomic analysis: Optimization and comparison of two coupling interfaces.
Gou MJ, Nys G, Cobraiville G, Demelenne A, Servais AC, Fillet M.J Chromatogr A. 2020 May 10;1618:460873. doi: 10.1016/j.chroma.2020.460873. 
Peer-reviewed publicationEvaluation of hydrophilic interaction liquid chromatography, capillary zone electrophoresis and drift tube ion-mobility quadrupole time of flight mass spectrometry for the characterization of phosphodiester and phosphorothioate oligonucleotides.
Demelenne A, Gou MJ, Nys G, Parulski C, Crommen J, Servais AC, Fillet M.J Chromatogr A. 2020 Mar 15;1614:460716. doi: 10.1016/j.chroma.2019.460716.
Peer-reviewed publicationMultidimensional performance assessment of micro pillar array column chromatography combined to ion mobility-mass spectrometry for proteome research.
Nys G, Cobraiville G, Fillet M.Anal Chim Acta. 2019 Dec 4;1086:1-13. doi: 10.1016/j.aca.2019.08.068. Epub 2019 Aug 30.
Peer-reviewed publicationTargeted proteomics reveals serum amyloid A variants and alarmins S100A8-S100A9 as key plasma biomarkers of rheumatoid arthritis.
Nys G, Cobraiville G, Servais AC, Malaise MG, de Seny D, Fillet M.Talanta. 2019 Nov 1;204:507-517. doi: 10.1016/j.talanta.2019.06.044.
Peer-reviewed publicationSelectivity evaluation of phenyl based stationary phases for the analysis of amino acid diastereomers by liquid chromatography coupled with mass spectrometry.
Moldovan RC, Bodoki E, Servais AC, Crommen J, Oprean R, Fillet M.J Chromatogr A. 2019 Apr 12;1590:80-87. doi: 10.1016/j.chroma.2018.12.068.
Peer-reviewed publicationCapillary electrophoresis, high-performance liquid chromatography, and thin-layer chromatography analyses of phenolic compounds from rapeseed plants and evaluation of their antioxidant activity.
Huang Y, Jansen O, Frédérich M, Mouithys-Mickalad A, Nys G, Servais AC, Crommen J, Jiang Z, Fillet M.J Sep Sci. 2019 Jan;42(2):609-618. doi: 10.1002/jssc.201800712.
Peer-reviewed publicationUltra-high-performance liquid chromatography-mass spectrometry method for neutrophil gelatinase-associated lipocalin as a predictive biomarker in acute kidney injury.
Ion V, Nys G, Cobraiville G, Cavalier E, Crommen J, Servais AC, Muntean DL, Fillet M. Talanta. 2019 Apr 1;195:668-675. doi: 10.1016/j.talanta.2018.11.050.
Peer-reviewed publicationKensert, Alexander, Collaerts, Gilles, Efthymiadis, Kyriakos, Desmet, Gert, & Cabooter, Deirdre. (2020). Deep Q-learning for the selection of optimal isocratic scouting runs in liquid chromatography. https://doi.org/10.1016/j.chroma.2021.461900
OtherPH Stefanuto, D Zanella, JF Focant. (2020). The ultimate untargeted technique. The Analytical Scientist, September 2020, 90, 42-46.
OtherPH Stefanuto, JF Focant. (2019). Comprehensive two-dimensional gas chromatography in industry: present situation and potential developments. Chimica Oggi – Chemistry Today – vol. 37(3) May/June 2019.
OtherWeggler, Benedikt; Dubois, Lena; Gawlitta, Nadine; Gröger, Thomas; Moncur, Jhon; Mondello, Luigi; Reichenbach, Steven; Tranchida, Peter; Zhao, Zhijun; Zimmermann, Ralf; Zoccali, Mariosimone; Focant, Jean-François. (2020). Benchmark GC×GC Data, Standards, Fragrances and Allergens. Harvard Dataverse, V1. https://doi.org/10.7910/DVN/KA5BTU

Conference participations:

AuthorConferenceStart date of the conferenceContribution
Priyanka Kumari, Thomas Van Laethem, Philippe Hubert, Marianne Fillet, Cédric Hubert, Pierre-Yves SacréChimiométrie01/02/2021Oral presentation
Alexander Kensert16th International Symposium on Hyphenated Techniques in Chromatography and Separation technology (HTC-16), Ghent, Belgium29/01/2020Poster presentation
Donatela Sadriaj16th International Symposium on Hyphenated Techniques in Chromatography and Separation technology (HTC-16), Ghent, Belgium29/01/2020Oral presentation
Deirdre CabooterPittcon 2020, Chicago, United States01/03/2020Oral presentation
Deirdre Cabooter27th International Symposium on Electrophoretic and Liquid Phase Separation Techniques (ITP-2020), Virtual02/11/2020Key note
Deirdre Cabooter10th Multidimensional Chromatography Workshop, Liège, Belgium21/01/2019Key note
Meriem Gaida16th International Symposium on Hyphenated Techniques in Chromatography and Separation technology (HTC-16), Ghent, Belgium, Ghent29/01/2020Poster presentation
Kinjal Bhatt16th International Symposium on Hyphenated Techniques in Chromatography and Separation technology (HTC-16), Ghent, Belgium, Ghent29/01/2020Poster presentation
Benedikt Weggler16th International Symposium on Hyphenated Techniques in Chromatography and Separation technology (HTC-16), Ghent, Belgium, Ghent29/01/2020Oral presentation
Jean-François Focant16th International Symposium on Hyphenated Techniques in Chromatography and Separation technology (HTC-16), Ghent, Belgium, Ghent29/01/2020Key note
Flavio Franchina16th International Symposium on Hyphenated Techniques in Chromatography and Separation technology (HTC-16), Ghent, Belgium, Ghent29/01/2020Oral presentation
Flavio Franchina16th International Symposium on Hyphenated Techniques in Chromatography and Separation technology (HTC-16), Ghent, Belgium, Ghent29/01/2020Poster presentation
Flavio Franchina16th International Symposium on Hyphenated Techniques in Chromatography and Separation technology (HTC-16), Ghent, Belgium, Ghent29/01/2020Poster presentation
Jean-François FocantAFSEP, Club IDF, Paris20/11/2019Key note
Jean-François Focant5th SBSE International Meeting, Paris23/09/2020Oral presentation
Flavio Franchina4th Imekofoods, Tervuren16/09/2020Oral presentation
Jean-François FocantThe 40th BMSS Annual Meeting, Manchester03/09/2020Oral presentation
Jean-François Focant67th ASMS ConferenCe on Mass speCtroMetry and allied topiCs, Atlanta02/06/2019Oral presentation
Benedikt Weggler10th MDCW, Liege21/01/2019Oral presentation
Zhuoheng Zhou16th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology (HTC-16), Ghent, Belgium29/01/2020Oral presentation
Gitte Coopmans48th International Symposium on High-Performance Liquid Phase Separations and Related Techniques (HPLC 2019), Milan, Italy16/06/2019Oral presentation
Cédric Hubert16th International Symposium on Hyphenated Techniques in Chromatography and Separation technology (HTC-16), Ghent, Belgium29/01/2020Oral presentation
Marianne Fillet16th International Symposium on Hyphenated Techniques in Chromatography and Separation technology (HTC-16), Ghent, Belgium29/01/2020Oral presentation
Vincent Pepermans16th International Symposium on Hyphenated Techniques in Chromatography and Separation technology (HTC-16), Ghent, Belgium29/01/2020Poster presentation
Zhuoheng Zhou16th International Symposium on Hyphenated Techniques in Chromatography and Separation technology (HTC-16), Ghent, Belgium29/01/2020Poster presentation
Raphael Ewonde Ewonde16th International Symposium on Hyphenated Techniques in Chromatography and Separation technology (HTC-16), Ghent, Belgium29/01/2020Poster presentation
Giacomo Russo16th International Symposium on Hyphenated Techniques in Chromatography and Separation technology (HTC-16), Ghent, Belgium29/01/2020Oral presentation
Adriaan Ampe16th International Symposium on Hyphenated Techniques in Chromatography and Separation technology (HTC-16), Ghent, Belgium29/01/2020Poster presentation
Giacomo Russo16th International Symposium on Hyphenated Techniques in Chromatography and Separation technology (HTC-16), Ghent, Belgium29/01/2020Poster presentation
Giacomo Russo48th International Symposium on High-Performance Liquid Phase Separations and Related Techniques, Milan, Italy16/06/2019Oral presentation
Giacomo Russo48th International Symposium on High-Performance Liquid Phase Separations and Related Techniques, Milan, Italy16/06/2019Poster presentation
Mathijs Baert15th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology, Cardiff, UK24/01/2018Oral presentation
Ravindra Hegade15th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology, Cardiff, UK24/01/2018Oral presentation
Mathijs Baert15th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology, Cardiff, UK24/01/2018Poster presentation
Thomas Van De Velde15th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology, Cardiff, UK24/01/2018Poster presentation
Kristina Wicht16th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology (HTC-16), Ghent, Belgium29/01/2020Oral presentation
Louise Decq16th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology (HTC-16), Ghent, Belgium29/01/2020Oral presentation
Zhanyao Hou16th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology (HTC-16), Ghent, Belgium29/01/2020Poster presentation
Jonas Veenhoven16th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology (HTC-16), Ghent, Belgium29/01/2020Poster presentation
Mathijs Baert16th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology (HTC-16), Ghent, Belgium29/01/2020Poster presentation
Kristina Wicht16th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology (HTC-16), Ghent, Belgium29/01/2020Poster presentation
Mathijs Baert48th International Symposium on High-Performance Liquid Phase Separations and Related Techniques, Milan, Italy16/06/2019Oral presentation
Giacomo Russo48th International Symposium on High-Performance Liquid Phase Separations and Related Techniques, Milan, Italy16/06/2019Oral presentation
Giacomo Russo48th International Symposium on High-Performance Liquid Phase Separations and Related Techniques, Milan, Italy16/06/2019Poster presentation
Mathijs Baert48th International Symposium on High-Performance Liquid Phase Separations and Related Techniques, Milan, Italy16/06/2019Poster presentation
Ravindra Hegade48th International Symposium on High-Performance Liquid Phase Separations and Related Techniques, Milan, Italy16/06/2019Poster presentation
Ewonde Ewonde R, Eßer D, Eeltink S16th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology (HTC-16), Ghent, Belgium29/01/2019Poster presentation
Gwenaël Nys, Gaël Cobraiville, Anne-Catherine Servais, Marianne Fillet.
26th International Symposium on Electroseparation and liquid-phase separation techniques
01/09/2019Oral presentation
Alice Demelenne, Marie-Jia Gou, Chloé Parulski, Anne-Catherine Servais, Marianne Fillet30th International Symposium on Pharmaceutical and Biomedical Analysis15/01/2018Oral presentation
Gwenaël Nys, Gaël Cobraiville, Anne-Catherine Servais, Marianne Fillet3rd International Symposium on Advances in Pharmaceutical Analysis26/10/2019Key note
Cindy Nix, Gwenaël Nys, Gaël Cobraiville, Marianne Fillet16th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology29/01/2020Oral presentation
Cindy Nix, Marie-Jia Gou, Gwenaël Nys, Gaël Cobraiville, Marianne Fillet6th International Ion Mobility Spectrometry (IMS) meeting18/02/2020Oral presentation
Marie-Jia Gou, Gwenaël Nys, Gaël Cobraiville, Alice Demelenne, Anne-Catherine Servais,
Jo Caers, Marianne Fillet
36th International Symposium on Microscale Separations and Bioanalysis27/09/2020Oral presentation
Marianne Fillet36th International Symposium on Microscale Separations and Bioanalysis27/09/2020Oral presentation
Marie-Jia Gou, Gwenaël Nys, Alice Demelenne, Gaël Cobraiville, Anne-Catherine Servais, Marianne Fillet30th International Symposium on Pharmaceutical and Biomedical Analysis15/09/2019Poster presentation
Paul Emonts, Anne-Catherine Servais, Marianne Fillet, Amandine Dispas36th International Symposium on Microscale Separations and Bioanalysis27/09/2029Poster presentation
Cindy Nix, Gael Cobraiville, Gwenael Nys, Marianne Fillet36th International Symposium on Microscale Separations and Bioanalysis27/09/2020Poster presentation

Training activities and supervision:

Title and yearAuthorSupervisor/PromotorInstitution
Determining ideal scouting runs for automated method development in liquid chromatography (2020)Gilles CollaertsDeirdre CabooterKU Leuven
Analytical development for volatolomics screening in biomedical applications (2020)Thibaut DejongJean-François FocantUniversité de Liège
Study of volatile prints for medical application (2021)Adele HeninJean-François FocantUniversité de Liège